Yini i-Osteosarcoma, Isifo Isimilo SikaSushant Singh Rajput Esinaso E-Dil Bechara?

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I-trailer yefilimu ebilindelwe kakhulu UDil bechara , Olingisa umlingisi ongasekho uSushant Singh Rajput no-Sanjana Sanghi odlala indawo yokuqala wadedelwa ngoMsombuluko (6 Julayi). Lesi sakhiwo sefilimu sigxile ohambweni lwabalingiswa ababili abaholayo, uKizie (Sanjana Sanghi), isiguli esinomdlavuza noManny (Sushant Singh Rajput), owasinda e-osteosarcoma, nokuthi umfundisa kanjani ukuphila impilo ngokugcwele. Ngokushesha nje lapho i-trailer yamafilimu iphumile, yathola izingoma ezivela kubalandeli nakosaziwayo. Nakhu okufanele ukwazi nge-osteosarcoma, isifo uSushant Singh Rajput anaso kule filimu.

Kuyini i-Osteosarcoma?

I-Osteosarcoma (OS) ebizwa nangokuthi i-osteogenic sarcoma uhlobo oluvame kakhulu lomdlavuza wamathambo othinta abantu abayi-3.4 kwisigidi emhlabeni wonke minyaka yonke. Kungumdlavuza wesithathu ovame kakhulu kubantu abasha. Izingane ezingaphansi kweminyaka engu-15 nazo zitholakala zine-osteosarcoma futhi akuvamile ezinganeni ezingaphansi kweminyaka emihlanu ubudala. Kodwa-ke, i-osteosarcoma ingakhula nganoma yisiphi isikhathi [1] .

I-Osteosarcoma iba namaseli akha amathambo. Imvamisa kuthinta amathambo amade njengalawo atholakala ezingalweni nasemilenzeni. I-Osteosarcoma yenzeka ikakhulukazi emaphethelweni amathambo amade, njenge-femur (ithambo lethanga) eduze kwamadolo, i-proximal tibia (shin bone) eduze kwamadolo ne-proximal humerus (i-upper arm bone) eduze kwehlombe.

Kodwa-ke, i-osteosarcoma nayo ingenzeka kwezinye izingxenye zomzimba ezinjengezinqe (okhalweni), emhlathini nasemathanjeni ehlombe evame kubantu abadala asebekhulile [okubili] , [3] .

Izimbangela ze-Osteosarcoma

Izimbangela ze-osteosarcoma azikacaci nokho, kunezici ezimbalwa okuthiwa ziyimbangela ye-osteosarcoma:

• Izakhi zofuzo - Ukukhubazeka kuzakhi zofuzo ze-p53 neRb (retinoblastoma) [4] .

• Ukukhula kwamathambo okusheshayo - Ingozi ye-Osteosarcoma nokukhula kwethambo okusheshayo kuxhunyanisiwe. Abantu abasha abanesibalo sokukhula bavame ukuba nengozi ephezulu yokuthola [5] .

• Ukuvezwa kwemisebe - Uma umuntu evezwe emisebeni yokwelashwa kolunye uhlobo lomdlavuza ebuntwaneni [6] .

Izinhlobo Ze-Osteosarcoma

Ngokusho kwe-American Cancer Society, i-osteosarcoma ingahlukaniswa ngale ndlela elandelayo:

• Ama-osteosarcomas aphezulu

• Ama-osteosarcomas asezingeni eliphansi

• Ama-osteosarcomas ebanga eliphakathi [7]

Izimpawu Ze-Osteosarcoma

• Ubuhlungu bamathambo noma obuhlangene [8] .

• Ukuvuvukala nokubomvu eduze kwethambo.

• Isigaxa esizwakala ngesikhumba

• Ngenkathi uphakamisa izinto uzwa ubuhlungu obukhulu ezingalweni.

• Ukuxhuga.

• Ithambo eliphukile.

Izici Zengozi Ye-Osteosarcoma

• Ukwelashwa kwangaphambilini kokwelashwa ngemisebe [9] .

• Isifo sikaPaget [9] .

• Izimo ezithile ezizuzwe njengefa.

Lapho Uzobona Udokotela

Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezingenhla, bonana nodokotela ngokushesha.

Ukuxilongwa Kwe-Osteosarcoma

Udokotela uzohlola ngokuphelele umzimba abuze ngezimpawu nomlando wezokwelapha. Ngemuva kwalokho, udokotela uzokwenza izivivinyo ezithile ukuthola i-osteosarcoma. Lezi zivivinyo zokuxilonga zifaka i-X-ray, i-MRI, i-CT scan, i-PET scan, ukuskena kwamathambo kanye ne-biopsy [10] .

Ukwelashwa Kwe-Osteosarcoma

• Ukuhlinzwa - Wonke amangqamuzana anomdlavuza namanye amaseli aphilile awazungezile akhishwa ethanjeni elithintekile. Kwezinye izimo, ukuhlinzwa kwezitho zomzimba kwenziwa ukukhipha wonke amangqamuzana anomdlavuza namanye amaseli aphilile azungezile ngokugcina isitho siqinile. Ukunqunywa kungenye inqubo yokuhlinzwa eyenziwa ngokususa konke noma ingxenye yengalo noma umlenze lapho kusabalale khona amangqamuzana omdlavuza. Umlenze wokufakelwa ube usufakwa esikhundleni salowo mlenze.

• Ukwelashwa ngamakhemikhali -Kuyindlela yokwelapha esetshenziselwa ukubulala amangqamuzana omdlavuza ngosizo lwemithi. Njengamanje, i-neoadjuvant chemotherapy inikezwa ngaphambi kokuhlinzwa nangemva kokuhlinzwa, kunikezwa i-adjuvant chemotherapy.

• Ukwelashwa ngemisebe - Le ndlela yokwelapha isebenzisa imisebe enamandla amakhulu ukubulala amangqamuzana omdlavuza. Ucwaningo lwango-2013 lubonise ukuthi ezinye iziguli ezine-osteosarcoma ezithola i-extracorporeal irradiation (ECI) zikhombise ukusebenza ngempumelelo ekuvikeleni lesi sifo ukuthi singaphinde senzeke futhi zehlisa nengozi yokutheleleka [ishumi nanye] .

• Ukwelashwa kwe-IFN - Ngenye inqubo yokwelashwa kwe-osteosarcoma esebenza ngokucindezela amaseli wesimila [12] .

Imibuzo evame ukubuzwa

U. Ngubani ongahle athole i-osteosarcoma?

TO . Izingane nentsha zisengozini enkulu. Kodwa-ke, abantu abadala asebekhulile bangasithola uma benesimo esivele sikhona njengesifo sikaPaget noma bake bathola ukwelashwa ngemisebe ngaphambilini.

U. Lingakanani inani lokusinda kwe-osteosarcoma?

TO . Izinga lokusinda kwe-osteosarcoma lenyuke laba ngaphezu kwamaphesenti angama-65. Kepha, uma i-osteosarcoma isakaze emaphashini noma kwamanye amathambo, izinga lokusinda liba liphansi.

U. Buzwa kanjani ubuhlungu be-osteosarcoma?

TO. Isiguli se-osteosarcoma singahlangabezana nobuhlungu obubuhlungu ethangeni noma ekuhlanganeni okuzungeze isimila.

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Ngithumele Nge-Imeyili Khombisa Esizeni