Kuyini iCarrageenan? Ukusetshenziswa Kwayo, Izinzuzo Nemiphumela Yayo

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ICarrageenan iyisengezo, esenziwe ngezingxenye zama-algae abomvu ahlukahlukene noma izimila zasolwandle. Isetshenziselwa ukujiya, ukuqinisa, nokugcina ukudla neziphuzo. Ebizwa nangokuthi i-Irish moss, isithako semvelo esisetshenziselwa imithi. Isetshenziselwa ukwelapha ukukhwehlela, i-bronchitis, isifo sofuba, nezinkinga zamathumbu, kanye nezilonda ezinamaphaphu, kube nokuphikisana okuningi maqondana nokusetshenziswa nokusetshenziswa kwezimila zasolwandle ^[1] .

Abanye basikisela ukuthi i-carrageenan ingadala ukuvuvukala, izinkinga zokugaya ukudla, njengokuqaqamba kwesifo samathumbu (IBD). Futhi ezimweni ezinzima, umdlavuza wamathumbu nawo. Iphinde isetshenziswe njengesiqinisi semithi, umuthi wokuxubha kanye nemikhiqizo yokudla. ICarrageenan nayo kuthiwa inenzuzo ekwehliseni isisindo ngempumelelo, kepha-ke, kufanele kwenziwe izifundo eziningi kulokho ^[okubili] .

ICarrageenan ayithathi hlangothi ngokudla okunomsoco futhi inokuqukethwe okuphezulu ngokweqile kwe-fiber, okwenza ingagayeki ngomzimba womuntu. Iqembu lama-polysaccharides afanayo afakwe sulphated, amandla alo okubopha amaprotheni yilokho okwenza kube lusizo enyameni nasemikhiqizweni yobisi ^[3] . Kunezinhlobo ezintathu eziyisisekelo: Iota Carrageenan, Kappa Carrageenan neLambda Carrageenan, zonke ezinokusetshenziswa okuhlukile nezingozi ezingaba khona eziphathelene nayo.

I-carrageenan esezingeni lokudla ikhishwa kolwandle olubomvu futhi icutshungulwe ngezinto ezine-alkaline. I-carrageenan eyonakele noma i-poligeenan akuphephile ukusetshenziswa, ngoba kungadala ukukhula kwamathumbu nezilonda emathunjini, nomdlavuza wekoloni ^[okubili] .

Ukusetshenziswa KweCarrageenan

Ukukhishwa kolwandle lwasolwandle kusetshenziselwa izinhloso ezimbili, umuthi ojwayelekile kanye nokufakwa kokudla ^[4] .

Njengomuthi ojwayelekile, i-carrageenan isetshenziselwa izixazululo ezisetshenziswa ekwelapheni ukukhwehlela, ukubanda, izinkinga zamathumbu njll Kusiza ukunciphisa izinhlungu nokuvuvukala kanye nemisebenzi njenge-laxative eningi futhi ilapha izilonda ezinamachaphazelo ^[5] .

Njengesengezo sokudla, i-carrageenan ayifaki inani lokudla okunomsoco noma ukunambitheka. Isakhiwo samakhemikhali esiyingqayizivele sokhula lwasolwandle siyenza ibe isibophezelo esisebenzayo, isiqinisi kanye ne-ejenti yokuqina. Kuvame ukusetshenziswa ekuxubeni amazinyo ^[6] .

Izinzuzo Zezempilo ZeCarrageenan

1. Kuqinisa impilo yamathumbu

Ngokuya ngocwaningo olwenziwe ngo-2015 ngemiphumela ye-carrageenan, kwaqinisekiswa ukuthi lungaba namandla okuba nomthelela ekwakhiweni kwemiphakathi yama-microbial ezuzisayo emkhakheni wokugaya ukudla, nakho okungathuthukisa amasosha omzimba akho. Kubuye kuthiwe kunekhono lokwelapha izilonda zesisu ezibangelwa utshwala ^[7] .

2. Kwehlisa amazinga aphezulu e-cholesterol

ICarrageenan itholwe inethonya elihle ekuphatheni amazinga we-cholesterol yakho. Uma ifakwe ekudleni kwakho kwansuku zonke, i-carrageenan ingasiza ekwehliseni i-cholesterol

namazinga e-lipid. Ingasetshenziswa futhi ekuvikeleni i-atherosclerosis kanye nesifo senhliziyo ^[8] .

3. Welapha amakhaza nomkhuhlane

Olunye ucwaningo luye lwaveza ukuthi ijeli ye-carrageenan iyakwazi ukubulala noma ukuvimbela amagciwane abanga umkhuhlane namakhaza. Isebenza ngokuvimbela amagciwane ukuthi anganamatheli odongeni lwamakhala, ngaleyo ndlela evimbele amandla ayo okusabalalisa ^[9] . Impahla yokulwa nolwandle yasolwandle isiza ukuvimbela ukulimala kumaseli akho.

4. Kuthuthukisa ukugaya

ICarrageenan ingaba lusizo ekusizeni uhlelo lwakho lokugaya ukudla ngokusekela ukunyakaza kwamathumbu okuvamile ^[10] . Ukuphuza isixazululo sezilwandle zasolwandle (ubilise izimila zasolwandle ngobisi noma emanzini) kungasiza ekuthuthukiseni ukugaya nokunyakaza kwamathumbu akho. Kuyasiza futhi ukuphatha ukucasuka kwesisu nokungahambi kahle.

Imiphumela emibi yeCarrageenan

Kwenziwe ucwaningo oluningi ekuqondeni umthelela omubi we-carrageenan, futhi kungendlela elandelayo ^[10] :

• Ukuqhakaza
• Ukungabekezelelani kwe-glucose
• Ukuvuvukala
• Ukungezwani kokudla
• Isifo samathumbu esicasulayo
• Umdlavuza wamakholoni
• Isilonda esikhulu samathumbu
• I-ulcerative colitis
• Ubuthi besisu nokukhubazeka kokuzalwa
• Umdlavuza ocacile
• Ukungabekezelelani kwe-glucose
• Ukumelana ne-insulin
• Umdlavuza wesibindi
• Ukucindezelwa komzimba

ICarrageenan ingadala ukuvuvukala okukhulu, okungaholela ekutheleleni okuvuvukala kwamathumbu, i-arthritis, i-tendonitis, i-cholecystitis engapheli, noma i-gallbladder ^{[ishumi nanye]} .

Ezinye izindlela eziphakanyisiwe esikhundleni se-carrageenan yizinkumbi zezinkumbi, i-gum arabic, i-alginate, i-guar gum ne-xanthan gum ^[12] , ^[13] .

1. [1]UNoda, H. (1993). Izinzuzo zezempilo nezakhiwo zokudla okunomsoco kwe-nori. Ijenali ye-Applied Phycology, 5 (2), 255-258.
2. [okubili]UXie, K., Miles, E. A., & Calder, P. C. (2016). Ukubuyekezwa kwezinzuzo ezingaba khona zezempilo zikaphayini womnqumo kanye ne-fatty acid pinolenic acid. Ijenali yokudla okusebenzayo, 23, 464-473.
3. [3]URaman, M., noDoble, M. (2015). I-κ-Carrageenan evela kulwelwe olubomvu lwasolwandle, iKappaphycus alvarezii – Ukudla okusebenzayo ukuvikela i-colon carcinogenesis.Izindaba zokudla okusebenzayo, 15, 354-364.
4. [4]Li, D., Wang, P., Luo, Y., Zhao, M., & Chen, F. (2017). Izinzuzo zezempilo zama-anthocyanins nezinqubo zamangqamuzana: Ukuvuselelwa kusuka eminyakeni eyishumi edlule Ukubuyekezwa okubalulekile kwisayensi yokudla nokondleka, 57 (8), 1729-1741.
5. [5]USánchez-González, C., Ciudad, C. J., Noe, V., & Izquierdo-Pulido, M. (2017). Izinzuzo zezempilo zama-walnut polyphenols: Ukuhlola okudlula iphrofayili yabo ye-lipid. Ukubuyekezwa okubalulekile kusayensi yokudla nokondleka, 57 (16), 3373-3383.
6. [6]Jeyakumari, A., Joseph, C., Zynudheen, A. A., & Anandan, R. (2016). Ukuhlolwa kwekhwalithi yesobho lezinhlanzi kufakwe ne-carrageenan.
7. [7]Umcibisheli, A. C., Muthukumar, S. P., & Halami, P. M. (2015). Amandla okulwa nokuvuvukala we-probiotic Lactobacillus spp. kwi-carrageenan eyenziwe nge-paw edema kumagundane e-Wistar.Iphephabhuku lamazwe omhlaba lama-macromolecule webhayoloji, 81, 530-537.
8. [8]Mao, L., Pan, Q., Hou, Z., Yuan, F., & Gao, Y. (2018). Ukwakhiwa kwamaprotheni we-soy isolate-carrageenan conjugates ngokusebenzisa ukuphendula kweMaillard kwe-microencapsulation yeBifidobacterium longum. Ukudla kwe-hydrocolloids, i-84, i-489-497.
9. [9]Shoaib, M., Shehzad, A., Omar, M., Rakha, A., Raza, H., Sharif, H. R., ... & Niazi, S. (2016). I-Inulin: Izakhiwo, izinzuzo zezempilo kanye nokusetshenziswa kokudla. Ama-polymer e-carbohydrate, 147, 444-454.
10. [10]USikandar, S., Gustavsson, Y., Marino, M. J., Dickenson, A. H., Yaksh, T. L., Sorkin, L. S., & Ramachandran, R. (2016). Imiphumela ye-intraplantar botulinum toxin-B ku-carrageenan - izinguquko ezibangelwa i-nociception ne-spinal phosphorylation ye-GluA1 ne-Akt. I-European Journal of Neuroscience, 44 (1), 1714-1722.
11. [ishumi nanye]UDomiati, S., El-Mallah, A., Ghoneim, A., Bekhit, A., & El Razik, H. A. (2016). Ukuhlolwa kwemisebenzi elwa nokuvuvukala, ye-analgesic, kanye nemiphumela emibi yezinye izakhi ze-pyrazole. I-Inflammopharmacology, i-24 (4), i-163-172.
12. [12]UChandel, P., Kumar, A., Singla, N., Kumar, A., Singh, G., & Gill, R. K. (2019). Ama-pyrazolines asuselwa ku-coumarin asuselwa ekunciphiseni ukuvuvukala kwe-carrageenan nge-COX-2 / pro-inflammatory cytokine inhibition.MedChemComm, 10 (3), 421-430.
13. [13]UDomínguez-Courtney, M. F., López-Malo, A., Palou, E., & Jiménez-Munguía, M. T. (2015). Ukusebenziseka kahle kwezakhiwo zemishini ye-carboxymethyl cellulose, i-carrageenan kanye / noma i-xanthan gls gels njengezinye izindlela zamaphilisi we-gelatin softgels. Ukwandiswa, 2 (11).

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